Bcl-2 Overexpression Abolishes Early Calcium Waving Preceding Apoptosis in NIH-3T3 Murine Fibroblasts

Bcl-2 overexpression inhibits tetrachlor

Bcl-2 overexpression inhibits tetrachlorohydroquinone-induced apoptosis in NIH3T3 cells: A possible mechanism for tumor promotion

✍ Yu-Ping Lin; Ben-Zhan Zhu; Ming-Chen Yang; Balz Frei; Ming-Hsiung Pan; Jen-Kun L 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 249 KB

## Abstract TCHQ is a major carcinogenic metabolite of the widely used wood preservative PCP. Recently, we found that TCHQ was a promoter in a mouse skin carcinogenesis model. However, the mechanism is still not clear. In this study, we showed that overexpression of Bcl‐2 effectively suppressed TCH