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bcl-2 immunoreactivity but not p53 accumulation associated with tumour response to radiotherapy in cervical carcinoma

โœ Scribed by M. Radhakrishana Pillai; P. G. Jayaprakash; M. Krishnan Nair

Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
258 KB
Volume
125
Category
Article
ISSN
1432-1335

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Background. In many tumors, the p53 gene has been mutated or deleted. p53 null mutant mice are prone to development of a variety of neoplasms at an early age. In head and neck cancer, p53 mutations are detected in most cases. p53 has been shown to induce growth arrest, differentiation, and death whe