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Bcl-2 deficiency deprives peripheral nerves of neurotrophic activity against injured optic nerve

✍ Scribed by Katarzyna Kotulska; Joanna Lewin-Kowalik; Magdalena Larysz-Brysz; Wiestaw Marcol; Zbigniew Fus


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
26 KB
Volume
77
Category
Article
ISSN
0360-4012

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Bcl-2 deficiency deprives peripheral ner
✍ Katarzyna Kotulska; Joanna Lewin-Kowalik; Magdalena Larysz-Brysz; WiesΕ‚aw Marcol πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 304 KB

## Abstract Optic nerve injury leads to retinal ganglion cell apoptosis, thus preventing fiber regeneration. Peripheral nerve grafts are known to promote survival and regeneration in injured adult mammalian central nervous system, including optic nerve, but the mechanisms of their activity remain u