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Bcl-2, bax and bcl-xL expression in human sensitive and resistant leukemia cell lines

✍ Scribed by Nuessler, V; Stötzer, O; Gullis, E; Pelka-Fleischer, R; Pogrebniak, A; Gieseler, F; Wilmanns, W


Book ID
110054355
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
178 KB
Volume
13
Category
Article
ISSN
0887-6924

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## Background: Inhibition of apoptosis, or programmed cell death, may be critical both in the development of cancer and in determining response to therapy. the authors examined the expression of two related apoptotic inhibitors, bcl-2 and bcl-xl, in pretreatment biopsies from a series of 42 patient