Tissue inhibitor of metalfoproteinase-2 (TIMP-2), a protease inhibitor that binds to the latent and active forms of 72 kDa type IV collagenase (gelatinase A), was found to inhibit the in vitro proliferation of human microvascular endothelial (HME) cells stimulated with bFGF and 5% serum. The maximal
✦ LIBER ✦
BCG-INDUCED URINARY CYTOKINES INHIBIT MICROVASCULAR ENDOTHELIAL CELL PROLIFERATION
✍ Scribed by PAVLOVICH, CHRISTIAN P.; KRÄLING, BIRGIT M.; STEWART, ROBERT J.; CHEN, XIAOHONG; BOCHNER, BERNARD H.; LUSTER, ANDREW D.; POPPAS, DIX P.; O’DONNELL, MICHAEL A.
- Book ID
- 123333829
- Publisher
- Lippincott Williams and Wilkins
- Year
- 2000
- Tongue
- English
- Weight
- 157 KB
- Volume
- 163
- Category
- Article
- ISSN
- 0022-5347
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## Abstract Hyperhomocysteinemia (HHcy) has been shown to induce endothelial dysfunction, an early event in the progression of atherosclerosis. However, the underlying mechanism of endothelial cell injury in HHcy has not been clearly elucidated. In this study, we examined the effect of homocysteine