In randomized clinical trials comparing treatment effects on diseases such as cancer, a multi-centre trial is usually conducted to accrue the required number of patients in a reasonable period of time. While we interpret the average treatment effect, it is necessary to examine the homogeneity of the
Bayesian statistics in oncology : A guide for the clinical investigator
โ Scribed by Michel Adamina; George Tomlinson; Ulrich Guller
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 181 KB
- Volume
- 115
- Category
- Article
- ISSN
- 0008-543X
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## BACKGROUND. In a randomized Phase I1 study, the authors evaluated the activity and toxicity of the new cisplatin, doxorubicin, and mitomycin C (PAM) comhination, that includes cisplatin (P) instead of 5-fluorouracil as in the 5-fluorouracil, doxorubicin, and mitomycin C (FAM) Combination, in pat