Two types of misclassification that commonly occur in family-genetic studies are distinguished: 1) nondifferential misclassification, in which the probability of error as to phenotype (presence or absence of psychiatric disorder) does not depend on exposure status (being kin to a case or control pro
BAYESIAN ESTIMATION OF RELATIVE RISK IN BIOMEDICAL RESEARCH
โ Scribed by RAMESH C. GUPTA; RICHARD A. ALBANESE; JOHN W. PENN; THOMAS J. WHITE
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 157 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1180-4009
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โฆ Synopsis
The relative risk is an important parameter in certain epidemiological studies. It is given by the ratio of the rates of developing a certain disease between the exposed and the control group. This paper deals with the Bayesian estimation of the relative risk using: (a) uniform [0,1] priors; (b) restricted uniform priors; (c) beta priors. The appropriateness of such priors is discussed in the medical setting and analytical expressions are obtained for the distributions of the relative risk in the above three cases. Data taken from the Air Force Health study are analysed and 95 per cent conยฎdence limits are presented for the three types of priors. Finally, for the Bayesian intervals, the estimated probabilities that the relative risk is greater than 1 are exhibited. # 1997 by
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