✦ LIBER ✦

Bayesian Estimation of Pharmacokinetic and Pharmacodynamic Parameters in a Mode-of-Action-Based Cancer Risk Assessment for Chloroform

✍ Scribed by Kai H. Liao; Yu-Mei Tan; Rory B. Conolly; Susan J. Borghoff; Michael L. Gargas; Melvin E. Andersen; Harvey J. Clewell III

Book ID: 109157698
Publisher: Springer
Year: 2007
Tongue: English
Weight: 481 KB
Volume: 27
Category: Article
ISSN: 1573-9147
DOI: 10.1111/j.1539-6924.2007.00987.x

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Physiologically based pharmacokinetic/ph

Physiologically based pharmacokinetic/pharmacodynamic modeling of chemical mixtures and possible applications in risk assessment

✍ Hisham A. El-Masri; Russell S. Thomas; Stephen A. Benjamin; Raymond S.H. Yang 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 729 KB

Evaluation of physiologically based phar

Evaluation of physiologically based pharmacokinetic models for use in risk assessment

✍ Weihsueh A. Chiu; Hugh A. Barton; Robert S. DeWoskin; Paul Schlosser; Chad M. Th 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 191 KB

## Abstract Physiologically based pharmacokinetic (PBPK) models are sophisticated dosimetry models that offer great flexibility in modeling exposure scenarios for which there are limited data. This is particularly of relevance to assessing human exposure to environmental toxicants, which often requ

Evaluating genotoxicity data to identify

Evaluating genotoxicity data to identify a mode of action and its application in estimating cancer risk at low doses: A case study involving carbon tetrachloride

✍ David A. Eastmond 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 118 KB 👁 1 views

Distinguishing the common components of

Distinguishing the common components of oil- and water-based metalworking fluids for assessment of cancer incidence risk in autoworkers

✍ Melissa C. Friesen; Sadie Costello; Sally W. Thurston; Ellen A. Eisen 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 303 KB 👁 2 views