✦ LIBER ✦

Bayesian approaches to the value of information: implications for the regulation of new pharmaceuticals

✍ Scribed by Karl Claxton

Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 51 KB
Volume: 8
Category: Article
ISSN: 1057-9230
DOI: 10.1002/(sici)1099-1050(199905)8:3<269::aid-hec425>3.0.co;2-d

No coin nor oath required. For personal study only.

✦ Synopsis

The current regulation of new pharmaceuticals is inefficient because it demands arbitrary amounts of information, the type of information demanded is not relevant to decision-makers and the same standards of evidence are applied across different technologies. Bayesian decision theory and an analysis of the value of both perfect and sample information is used to consider the efficient regulation of new pharmaceuticals. This type of analysis can be used to decide whether the evidence in an economic study provides 'sufficient substantiation' for an economic claim, and assesses whether evidence can be regarded as 'competent and reliable'.

📜 SIMILAR VOLUMES

A Bayesian approach to the analysis of e

A Bayesian approach to the analysis of environmental fate and behaviour data for pesticide registration

✍ Worrall, Fred; Wooff, David A.; Seheult, Allan H.; Coolen, Frank P. A. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 269 KB 👁 1 views

With the harmonisation of data requirements for pesticide registration under EC Directive 91/414 there is need for progress on the techniques used to analyse such data and so help make consistent the judgements applied by national regulatory authorities. This paper proposes a Bayesian technique for

Value Creation (Strategies for the Chemi

Value Creation (Strategies for the Chemical Industry) || An Approach to Determining the Long-term Attractiveness of Commodity Chemical Businesses

✍ Budde, Florian; Felcht, Utz-Hellmuth; FrankemÃ¶lle, Heiner 📂 Article 📅 2008 🏛 Wiley-VCH Verlag GmbH & Co. KGaA ⚖ 265 KB 👁 1 views

Development and application of a new app

Development and application of a new approach to the construction of external equivalents for use by power system stabilizing controllers

✍ Masashi Saeki; Hideo Matsuoka; Yasutaro Nagae; Minoru Tanaka; Kazuya Omata; Masa 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 229 KB 👁 2 views

A new approach to the effective preparat

A new approach to the effective preparation of plasma samples for rapid drug quantitation using on-line solid phase extraction mass spectrometry

✍ Jianmei Ding; Uwe D. Neue 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 1 views

A procedure that permits rapid development of an optimized solid phase extraction (SPE) method for the analysis of drugs in plasma by on-line solid phase extraction-mass spectrometry (SPE-MS) has been developed. This procedure employs the concept of manipulating the pH and the percentage of organic