Bayesian adaptive clinical trials: a dre
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Sylvie Chevret
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Article
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2011
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John Wiley and Sons
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English
β 396 KB
Adaptive or βflexibleβ designs have emerged, mostly within frequentist frameworks, as an effective way to speed up the therapeutic evaluation process. Because of their flexibility, Bayesian methods have also been proposed for Phase I through Phase III adaptive trials; however, it has been reported t