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BAY K 8644 stimulates glucose-dependent rise of cytoplasmic Ca2+in hyperpolarized pancreatic β-cells

✍ Scribed by E. Gylfe


Book ID
112274899
Publisher
Springer-Verlag
Year
1992
Tongue
English
Weight
336 KB
Volume
345
Category
Article
ISSN
0028-1298

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The effect of carbachol on the cytoplasmic Ca2+ concentration [( Ca2+]i) was studied in insulin-releasing mouse pancreatic beta cells hyperpolarized by the K(+)-channel-activating agent diazoxide. By mobilizing intracellular Ca2+, carbachol induced an initial [Ca2+]i transient, which was more than t