Bay K 8644 enhances slow inward and outward currents in voltage-clamped frog skeletal muscle fibres

The depressing effect of tetracaine and

The depressing effect of tetracaine and ryanodine on the slow outward current correlated with that of contraction in voltage-clamped frog muscle fibres

✍ Mohammad Nasri-Sebdani; Flavien Traoré; Christian Cognard; Daniel Potreau; Jean 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 687 KB

The effects of tetracaine (10-50 laM) and ryanodine (0.1 -10 gM) were tested on the slow outward K + current (Iso) and the mechanical tension of isolated frog muscle fibres in a voltage-clamp device (double mannitol-gap) connected to a mechanoelectric transducer. In the concentration range tested, b