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Bax is essential for mitochondrion-mediated apoptosis but not for cell death caused by photodynamic therapy

✍ Scribed by Chiu, S-M; Xue, L-Y; Usuda, J; Azizuddin, K; Oleinick, N L


Book ID
109997776
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
243 KB
Volume
89
Category
Article
ISSN
0007-0920

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## Abstract Bcl‐2 family proteins are critical for the regulation of apoptosis, with the pro‐apoptotic members Bax essential for the release of cytochrome __c__ from mitochondria in many instances. However, we found that Bax was activated after mitochondrial depolarization and the completion of cyt