In a previous study, we showed that geranylgeraniol (GGO) is a potent inducer of apoptosis in human leukemia cells, including HL60 promyelocytic leukemia cells. The present study describes the effects of activators of protein kinase C (PKC) on GGO-induced apoptosis in various lines of leukemia cells
β¦ LIBER β¦
Bax Activation and Induction of Apoptosis in Human Keratinocytes by the Protein Kinase C delta Catalytic Domain
β Scribed by Sitailo, Leonid A.; Tibudan, Shalini S.; Denning, Mitchell F.
- Book ID
- 110733279
- Publisher
- Nature Publishing Group
- Year
- 2004
- Tongue
- English
- Weight
- 958 KB
- Volume
- 123
- Category
- Article
- ISSN
- 0022-202X
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## Abstract Nitric oxide (NO) can regulate chondrocyte activities. This study was aimed to evaluate the molecular mechanisms of NO donor sodium nitroprusside (SNP)βinduced insults to human chondrocytes. Exposure of human chondrocytes to SNP increased cellular NO levels but decreased cell viability