Exogenous alkaline phosphatase for the t
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Milan Lukas; Pavel Drastich; Michal Konecny; Paolo Gionchetti; Ondrej Urban; Fra
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Article
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2010
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John Wiley and Sons
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English
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Background: Increased activity of intestinal alkaline phosphatase (AP) occurs locally in patients with ulcerative colitis (UC), aimed at repairing inflammatory tissue damage. We evaluated the safety and preliminary efficacy of exogenous AP administered to patients with UC in an open-label, first-in-