## Abstract The constitutively active Bcr‐Abl tyrosine kinase plays a crucial role in chronic myelogenous leukemia (CML) pathogenesis. The Bcr‐Abl protein induces the upregulation of proto‐oncogene c‐Jun, which is involved in Bcr‐Abl transforming activity in Bcr‐Abl positive cells. Recent studies r
✦ LIBER ✦
Basic fibroblast growth factor inhibits p38-mediated cell differentiation and growth inhibition by activin A but not by histone deacetylase inhibitors in CML cells
✍ Scribed by Chun-Hsin Chen; John Yi-Chung Lin; Fu-Hwa Liu; Ju-Ling Chang; Huei-Mei Huang
- Book ID
- 105989041
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 239 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0939-5555
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## Abstract Basic fibroblast growth factor (basic FGF) has pivotal roles in the function of various cell types. Here, we report the effects of basic FGF in the regulation of dental pulp stem cell (DPSC) behaviors including maintaining stemness and directing differentiation. Cells isolated from huma