We previously showed that basic fibroblast growth factor (bFGF)-induced activation of protein kinase C (PKC) via phosphatidylinositol-hydrolyzing phospholipase C and phosphatidylcholine-hydrolyzing phospholipase D suppresses interleukin-6 (IL-6) synthesis by bFGF itself in osteoblast-like MC3T3-E1 c
โฆ LIBER โฆ
Basic Fibroblast Growth Factor Induces Interleukin-6 Synthesis in Osteoblasts: Autoregulation by Protein Kinase C
โ Scribed by Osamu Kozawa; Atsushi Suzuki; Toshihiko Uematsu
- Book ID
- 114284058
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 418 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0898-6568
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## Abstract Fibronectin (Fn) is involved in early stages of bone formation and basic fibroblast growth factor (bFGF) is an important factor regulating osteogenesis. bFGF increased Fn expression, which was attenuated by phosphatidylinositol phospholipase inhibitor (U73122), protein kinase C inhibito
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