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Basic fibroblast growth factor (bFGF) enhances retinal ganglion cells’ survival and promotes axonal growth of rat transected optic nerve

✍ Scribed by P. Cuevas; F. Carceller; A. Esteban; A. Baird; R. Guillemin

Book ID: 114782918
Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 72 KB
Volume: 79
Category: Article
ISSN: 0001-6314
DOI: 10.1111/j.1600-0404.1989.tb03770.x

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## Abstract Application of basic fibroblast growth factor (FGF‐2) to the optic nerve after axotomy promotes the survival of retinal ganglion cells (RGCs) in the frog __Rana pipiens__ and results in a rapid up‐regulation of brain‐derived neurotrophic factor (BDNF) and TrkB synthesis by the RGCs. Her