Basic Concepts in Medicinal Chemistry

✍ Scribed by Marc W. Harrold, Robin M. Zavod

• Publisher: ASHP
• Year: 2022
• Tongue: English
• Leaves: 544
• Edition: 3
• Category: Library

✦ Synopsis

Designed to help students incrementally build their knowledge of fundamental concepts of medicinal chemistry and their applications to therapeutic decisions, it is progressively organized. Specific sections of the text have been updated to make potentially confusing concepts easier to understand. Numerous examples and review questions further reinforce learning and analytical skills.

This updated and expanded edition of the popular textbook, Basic Concepts in Medicinal Chemistry, has been enhanced with new subject material, numerous self-assessment tools, and special features to advance and strengthen the learning process.

New in the Third Edition

• Enhanced explanations, discussions, and examples in many key chapters
• Additional summary tables to help readers better select the proper drug binding interaction
• Expanded discussion on Pharmacogenomics, including multiple specific examples
• Updated examples throughout the text to include a wider range of drugs and drug classes
• Increased focus on application of concepts to therapeutic decisions and pharmacy practice

 

✦ Table of Contents

Cover
Title
Copyright
TABLE OF CONTENTS
ACKNOWLEDGMENTS
PREFACE
ABBREVIATIONS USED IN THIS TEXT
INTRODUCTION
FUNCTIONAL GROUP CHARACTERISTICS AND ROLES
IDENTIFYING ACIDIC AND BASIC FUNCTIONAL GROUPS
SOLVING pH AND pK
SALTS AND SOLUBILITY
DRUG BINDING INTERACTIONS
STEREOCHEMISTRY AND DRUG ACTION
DRUG METABOLISM
STRUCTURE ACTIVITY RELATIONSHIPS AND BASIC CONCEPTS IN DRUG DESIGN
WHOLE MOLECULE DRUG EVALUATION
ANSWERS TO CHAPTER QUESTIONS