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Basic calcium phosphate crystal-induced collagenase production: role of intracellular crystal dissolution

✍ Scribed by Geraldine M. McCarthy; Herman S. Cheung; Susan M. Abel; Lawrence M. Ryan

Book ID
114476043
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
177 KB
Volume
6
Category
Article
ISSN
1063-4584

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πŸ“œ SIMILAR VOLUMES

Basic calcium phosphate crystals cause c
Basic calcium phosphate crystals cause coordinate induction and secretion of collagenase and stromelysin
✍ Geraldine M. McCarthy; Peter G. Mitchell; Janine A. Struve; Herman S. Cheung πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 815 KB

Synovial fluid basic calcium phosphate crystals (BCP) are often found in severely degenerated joints. Crystalline BCP is a growth factor stimulating fibroblast mitogcnesis and acting as a competence factor similar to platelet-derived growth factor. In human fibroblasts (HF), the synthesis of collage