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Base-induced rearrangement of ethane-2-chloro-1-hydroxy-1,1-diphosphonic acid

✍ Scribed by Quimby, O. T.; Cilley, W. A.; Prentice, J. B.; Nicholson, D. Allan

Book ID
121318748
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
414 KB
Volume
38
Category
Article
ISSN
0022-3263

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## Abstract Systemic treatment with disodium ethane‐hydroxy‐1, 1‐diphosphonate is ineffective in inhibiting the calcergenic reactions induced in mouse skin by the lanthanides. In contrast, disodium dichloromethylene diphosphonate prevents lanthanide calcergy induced by 12 of the 15 compounds tested