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Base Excision Repair of Oxidative DNA Damage Activated by XPG Protein

✍ Scribed by Arne Klungland; Matthias Höss; Daniela Gunz; Angelos Constantinou; Stuart G Clarkson; Paul W Doetsch; Philip H Bolton; Richard D Wood; Tomas Lindahl


Book ID
117736144
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
250 KB
Volume
3
Category
Article
ISSN
1097-2765

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✍ Sankar Mitra; Istvan Boldogh; Tadahide Izumi; Tapas K. Hazra 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 204 KB 👁 2 views

## Abstract Oxidative damage represents the most significant insult to organisms because of continuous production of the reactive oxygen species (ROS) in vivo. Oxidative damage in DNA, a critical target of ROS, is repaired primarily via the base excision repair (BER) pathway which appears to be the