Base assisted substitution of α-amidoalkyl sulfones by nitromethane anion. A new entry to functionalized α-amino acids

✍ Scribed by Roberto Ballini; Marino Petrini

• Book ID: 104261553
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 223 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00770-4

✦ Synopsis

The nitromethane anion reacts with ot-amidoalkyl sulfones in TI-IF affording the corresponding nitro derivatives that upon oxidation with alkaline potassium permanganate give the corresponding N-protected ¢t-araino acids