Barrett’s Esophagus

✍ Scribed by Reginald V. N. Lord (auth.), Hugo W. Tilanus, Stephen E. A. Attwood F.R.C.S. (eds.)

• Publisher: Springer Netherlands
• Year: 2001
• Tongue: English
• Leaves: 396
• Edition: 1
• Category: Library

✦ Synopsis

Barrett's Esophagus gives an extensive overview written by the world's leading experts covering the epidemiology, gastroenterology and surgery, as well as the molecular basis of:

• the precursor lesions leading to the development of Barrett's epithelium;
• the unique characteristics of Barrett's esophagus;
• the consequences of malignant degeneration, i.e. adenocarcinoma.

All aspects in terms of diagnosis, secondary prevention, multimodality, medical and surgical treatment are elucidated.

✦ Table of Contents

Front Matter....Pages i-xvii
Norman Barrett and the Esophagus....Pages 1-15
Anatomy and Embryology of the Esophagus....Pages 17-30
Cell Biology of the Esophageal Epithelium....Pages 31-49
Normal Physiology of the Esophagus....Pages 51-55
Pathophysiology of Gastro-Esophageal Reflux Disease....Pages 57-70
The Natural History of Gastro-Esophageal Reflux Disease....Pages 71-80
Helicobacter Pylori and Reflux Disease....Pages 81-105
Acid and Bile in the Esophagus....Pages 107-120
Endoscopic Classification of Gastro-esophageal Reflux Disease....Pages 121-135
Optimal Surgical Therapy for Anti Reflux Disease....Pages 137-147
Surgical Treatment of Duodeno-Gastro Esophageal Reflux....Pages 149-158
Histopathology of Barrett’s Esophagus....Pages 159-166
The Metaplasia-Dysplasia-Carcinoma Sequence of Barrett’s Esophagus....Pages 167-180
Genetic Alterations....Pages 181-209
Endoscopic Surveillance....Pages 211-216
Short Segment Barrett’s Esophagus and Intestinal Metaplasia at the Gastroesophageal Junction....Pages 217-229
Prevention of Cancer by Control of Reflux....Pages 231-238
Prevention of Cancer in Barrett’s by Ablation....Pages 239-258
The Role of Ablation in the Management of High-Grade Dysplasia....Pages 259-272
Surgical Treatment of High-Grade Dysplasia and Superficial Carcinoma....Pages 273-280
Epidemiology of Barrett’s Esophagus and Adenocarcinoma....Pages 281-290
Adenocarcinoma in Barrett’s Esophagus: Signs, Symptoms and Endoscopic Appearance....Pages 291-295
Adenocarcinoma in Barrett’s Esophagus — Classification and Staging....Pages 297-306
Diagnosis and Implications of Bone Marrow Micrometastases....Pages 307-315
Indications and Outcome of Esophageal Resection....Pages 317-324
Transhiatal Esophagectomy....Pages 325-333
Resection of Esophageal Carcinoma: The Role of Lymph Node Dissection....Pages 335-346
Videoendoscopic Esophagectomy for Cancer....Pages 347-355
Management of Postoperative Complications....Pages 357-366
Multimodality in the Management of Adenocarcinoma of the Esophagus....Pages 367-376
Endoscopic Management of Dysphagia from Esophageal Cancer....Pages 377-386
Function and Quality of Life after Esophageal Resection....Pages 387-392
Back Matter....Pages 393-395

✦ Subjects

Gastroenterology; Abdominal Surgery; Oncology; Pathology