Barium enema findings in a case of Langerhans cell histiocytosis involving the colon
β Scribed by B. S. Gilmore; M. Cohen
- Publisher
- Springer-Verlag
- Year
- 1993
- Tongue
- English
- Weight
- 316 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0301-0449
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Previous reports of patients with Langerhans' cell histiocytosis have shown characteristics of osteolytic lesion, visceral involvement and organ dysfunction. We report a 2-year-old boy who was diagnosed as Langerhans' cell histiocytosis with a prominent hepatomegaly. X-Radiogram, computed tomography
Langerhans' cell histiocytosis (LCH) is characterized by an accumulation and/or proliferation of cells with a Langerhans' cell (LC) phenotype. The aetiology and pathogenesis of LCH are unknown; it is suggested that LCH is caused by an immunological dysregulation. Production of cytokines is a central