Baker's yeast as a tool for the development of antifungal drugs which target cell integrity – an update

Baker's yeast as a tool for the developm

Baker's yeast as a tool for the development of antifungal kinase inhibitors—targeting protein kinase C and the cell integrity pathway

✍ Jürgen J. Heinisch 📂 Article 📅 2005 🏛 Elsevier Science 🌐 English ⚖ 681 KB

Today, the yeast Saccharomyces cerevisiae is probably the best-studied eukaryotic organism. This review first focusses on the signaling process which is mediated by the unique yeast protein kinase C (Pkc1p) and a downstream mitogen-activated protein kinase (MAPK) cascade. This pathway ensures cellul