Impaired expression and function of toll
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Serena Chang; Karen Kodys; Gyongyi Szabo
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Article
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2009
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John Wiley and Sons
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English
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Hepatitis C virus (HCV) interferes with interferon (IFN)-mediated innate immune defenses. Toll-like receptor (TLR) 7 agonists robustly inhibit HCV infection. We hypothesize that HCV infection may interfere with the expression and/or function of TLR7, a sensor of single-stranded RNA. We identified re