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Bacteriorhodopsin: The influence of the cyclohexene-ring methyls

✍ Scribed by J. M. L. Courtin; L. Verhagen; P. L. Biesheuvel; J. Lugtenburg; R. L. van der Bend; K. van Dam


Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
830 KB
Volume
106
Category
Article
ISSN
0165-0513

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The influence of the 5-methyl group in b
✍ M. Groesbeek; E. F. J. de Vries; J. A. Berden; J. Lugtenburg 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 594 KB

## Abstract All‐__E__‐5‐bromo‐5‐demethylretinal was prepared in 6% yield starting from 4,4‐dimethyl‐2‐cyclohexenone via 2‐bromo‐6,6‐dimethyl‐1‐cyclohexenecarboxaldehyde. The crucial step in the preparation of the intermediate is a 2,3 Wittig rearrangement. 5‐Bromo‐5‐demethylbacteriorhodopsin is eas