Bacterial Virulence: Basic Principles, Models and Global Approaches (Infection Biology (VCH))

✍ Scribed by Philippe Sansonetti (editor)

• Publisher: Wiley-VCH Verlag GmbH
• Year: 2010
• Tongue: English
• Leaves: 329
• Series: Infection Biology (VCH)
• Edition: 1
• Category: Library

✦ Synopsis

Starting with basic principles, this reference and handbook discusses examples of the most advanced models of bacterial infection with regard to their value as paradigms to understand the molecular cross talks between microbes and their host and tissue targets. It adopts a very forward-looking, advanced approach, placing special emphasis on the main global challenges facing scientists today, such as pathogenicity vs. commensalisms, infections in immunocompromised hosts and species specificity issues. Bacterial Virulence: Basic Principles, Models and Global Approaches is the second title in Wiley-Blackwell's 'Infection Biology Handbook Series'. The first is Aids and Tuberculosis: A Deadly Liaison, edited by two of the most accomplished experts in this area, Prof. Dr. Dr. h.c. Stefan Kaufmann at the Max-Planck Institute for infectious diseases in Berlin, Germany, and Prof. Dr. Bruce Walker, director of the Ragon Institute of MGH, MIT and Harvard in Boston, USA.

✦ Table of Contents

Front Matter
How Bacterial Pathogens were Constructed
Antimicrobial Mechanisms of Neutrophils
Infection - The Route from Inflammation to CancerH. pylori
Host-Pathogen Relationship in Skin and Soft Tissue Infections Caused by Group A streptococcusStaphylococcus aureus
Mechanisms of Meningeal Invasion by Septicemic Extracellular Pathogens: The Examples of Neisseria meningitidisStreptococcus agalactiaeEscherichia coli
Two Important Bacterial Pathogens Causing Community Acquired Pneumonia: Streptococcus pneumoniaeLegionella pneumophila
The Salmonella
: from Molecular Insight to Therapeutic DiscoveryChlamydia
The Gut Microbiota and its Contribution to Homeostasis
Anatomy of the Gut Barrier and Establishment of Intestinal Homeostasis
Dynamic Imaging Technologies to Explore Infectious Processes at the Cellular, Tissue and Organ Level
The Issue of Species Specificity of Bacterial Infection, How to Address it Experimentally
Index