Bacterial isolates from patients with preterm labor with and without preterm rupture of the fetal membranes

✍ Scribed by H. Mikamo; Y. Sato; Y. Hayasaki; K. Kawazoe; Y.X. Hua; T. Tamaya

• Publisher: Hindawi Publishing Corporation
• Year: 1999
• Tongue: English
• Weight: 61 KB
• Volume: 7
• Category: Article
• ISSN: 1064-7449
• DOI: 10.1002/(sici)1098-0997(1999)7:4<180::aid-idog5>3.0.co;2-1

✦ Synopsis

Objective: The aim of this study is to describe the bacterial flora of women in preterm labor with or without premature rupture of membranes.

Methods: Retrospective studies of 239 patients with preterm labor were performed.

Results: One hundred and twenty-three of 239 patients with preterm labor (51.5%) had bacterial vaginosis. Seventy of the 239 patients with preterm labor (29.3 %) developed premature rupture of the membranes (preterm PROM). Of the 70 patients with preterm PROM, 51 (72.9%) had bacterial vaginosis. Therefore, 51 of the 123 patients with bacterial vaginosis (41.5%) developed preterm PROM. An increased number of organisms detected from the vaginal discharge in patients with preterm labor was associated with preterm PROM by Cochran-Armitage test. An increased number of organisms detected from the vaginal discharge in patients with preterm labor complicated with bacterial vaginosis was significantly associated with preterm PROM by Cochran-Armitage test.

Conclusions: In preterm labor, the number of different species detected in the vagina provide sensitive and specific prediction of preterm PROM in patients with preterm labor.