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Bacterial DNA-Induced NK Cell IFN-γ Production Is Dependent on Macrophage Secretion of IL-12

✍ Scribed by Jacqueline H. Chace; Nick A. Hooker; Kristy L. Mildenstein; Arthur M. Krieg; John S. Cowdery


Book ID
112241014
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
200 KB
Volume
84
Category
Article
ISSN
1090-2341

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## Abstract Interleukin‐12 (IL‐12) is a disulfide‐linked p40‐p35 heterodimeric cytokine and plays a key role in linking innate cellular immunity to an adaptive Th1 response against pathogens and tumor cells and in counteracting a Th2 immune response. The pathogenesis of Hodgkin's disease (HD) is pa