An analysis of anticonvulsant actions of
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Keiko Sato; Kiyoshi Morimoto; Motoi Okamoto; Yasushi Nakamura; Saburo Otsuki; Mi
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Article
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1990
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Elsevier Science
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English
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The anticonvulsant action of progabide, an agonist of gamma-aminobutyric acid (GABA)A and GABAB receptors, was investigated in the kindling model of epilepsy in rats. Progabide shortened afterdischarge durations and attenuated the severity of the accompanying convulsive responses in previously kindl