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Backbone dynamics of the EGF-like domain of heregulin-α

✍ Scribed by Wayne J. Fairbrother; Jun Liu; Paul I. Pisacane; Mark X. Sliwkowski; Arthur G. Palmer III


Book ID
115628592
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
707 KB
Volume
279
Category
Article
ISSN
0022-2836

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## Abstract Heparin‐binding EGF‐like growth factor (HB‐EGF), which belongs to the EGF‐family of growth factors, was isolated from the conditioned medium of macrophage‐like cells. To investigate the effect of __N__‐ and __C__‐terminal residues of the EGF‐like domain of HB‐EGF in the binding affinity