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Backbone dynamics of complement control protein (CCP) modules reveals mobility in binding surfaces

โœ Scribed by Joanne M. O'Leary; Krystyna Bromek; Gordon M. Black; Stanislava Uhrinova; Christian Schmitz; Xuefeng Wang; Malgorzata Krych; John P. Atkinson; Dusan Uhrin; Paul N. Barlow


Book ID
111752328
Publisher
Cold Spring Harbor Laboratory Press
Year
2004
Tongue
English
Weight
341 KB
Volume
13
Category
Article
ISSN
0961-8368

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Mapping of regions within the vaccinia v
โœ Scott A. Smith; R. Sreenivasan; Gunasekaran Krishnasamy; Ken W. Judge; Krishna H ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 636 KB

The vaccinia virus complement control protein (VCP) is involved in modulating the host inflammatory response by blocking both pathways of complement activity through its ability to bind C3b and C4b. Other activities arise from VCP's ability to strongly bind heparin. To map regions within VCP involve