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Back to the beginning – the quest for thymic epithelial stem cells

✍ Scribed by Jeremy B. Swann; Thomas Boehm

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
84 KB
Volume
37
Category
Article
ISSN
0014-2980

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Stem cell‐based therapies hold much promise for the rejuvenation of aged or damaged tissues; however, before such cells can be used therapeutically, they must first be accurately identified. In this issue of the European Journal of Immunology it is reported that MTS24, a marker previously associated with progenitor cells of the thymic epithelium, fails to accurately identify epithelial cell populations with the ability to reconstitute a functional thymus. This finding demonstrates that much progress needs to be made before thymic epithelial stem cells can be harnessed for clinical benefit.

See accompanying article: http://dx.doi.org/10.1002/eji.200737275

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