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BACE1 inhibition as a therapeutic strategy for Alzheimer's disease

✍ Scribed by Vassar, Robert

Book ID: 122327878
Publisher: Elsevier Science
Year: 2014
Tongue: English
Weight: 49 KB
Volume: 35
Category: Article
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2014.01.119

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## Abstract Alzheimer's disease (AD) is characterized by progressive loss of memory and cognition. Our laboratory and many others have shown that the AD brain is under extensive oxidative stress. Numerous therapeutic approaches to AD therapy have been hypothesized. Among these are exogenous antioxi