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B7-H1 up-regulated expression in human pancreatic carcinoma tissue associates with tumor progression

✍ Scribed by Lei Geng; Dongsheng Huang; Junwei Liu; Yigang Qian; Junfang Deng; Donglin Li; Zhenhua Hu; Jian Zhang; Guoping Jiang; Shusen Zheng

Publisher: Springer-Verlag
Year: 2008
Tongue: English
Weight: 380 KB
Volume: 134
Category: Article
ISSN: 1432-1335
DOI: 10.1007/s00432-008-0364-8

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## Abstract ## BACKGROUND PD‐L1 (programmed death ligand 1, B7‐H1) is a cell surface glycoprotein that can impair T‐cell function. PD‐L1 is aberrantly expressed by multiple human malignancies and has been shown to carry a highly unfavorable prognosis in patients with kidney cancer. The role of PD‐