B390 Rare IgH/14q32 Translocations in Multiple Myeloma
β Scribed by Michaux, LM; Vekemans, MC; Lemmens, H; Delforge, M; Lemoine, F; Vandenberghe, P; Wlodarska, I
- Book ID
- 118629496
- Publisher
- CIG Media Group, LP.
- Year
- 2009
- Tongue
- English
- Weight
- 95 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1557-9190
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## Abstract Translocations involving the immunoglobulin heavyβchain genes are frequent in multiple myeloma (MM), which can be separated into two groups according to the chromosome number pattern. 14q32 translocations 14q32t are more frequent in hypodiploid than in hyperdiploid karyotypes. However,
## Abstract Multiple myeloma (MM) is a malignancy of the plasma cells (PCs) characterized by a wide variety of genetic and chromosomal abnormalities. In recent years, major attention was drawn to the significance of chromosomal aberrations involving chromosome arm 13q and the __IGH__ region on chro