## Abstract The role of antibodyโforming cell (AFC) blockade in the genesis of haptenโspecific tolerance induced by hapten (2,4โdinitrophenyl)โcoupled pneumococcal polysaccharide (DNPโlysโS3) was investigated. Tolerizing doses of DNPโlysโS3 given to mice making antibodies to DNPโhemocyanin a day be
โฆ LIBER โฆ
B cell tolerance induced by polymeric antigens. VI. Kinetics and reversibility of the inhibition of antibody-forming cells by antigen
โ Scribed by G. G. B. Klaus
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 687 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0014-2980
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## Anti -CD3 ุ anti-B-cell antigen bispecific monoclonal antibodies (bsAbs) can redirect T-cell-mediated lysis toward malignant B cells. Clinical trials with CD3-based bsAbs have shown toxicity in patients which is likely related to nonspecific T-cell activation and targeting. Our current studies