B-cell responses to intravenous glucose and glucagon in non-diabetic twins of patients with Type 1 (insulin-dependent) diabetes mellitus
β Scribed by D. A. Heaton; N. R. Lazarus; D. A. Pyke; R. D. G. Leslie
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 388 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0012-186X
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Glucose tolerance and insulin secretion were studied in two groups of non-diabetic identical twins of recently-diagnosed Type 1 (insulin-dependent) diabetic patients: (1) a group of 5 twins with islet cell antibodies, and (2) a group of 6 twins without. Despite similar fasting glucose, insulin and C
Preventive treatment of Type 1 (insulin-dependent) diabetes presupposes early and accurate diagnosis of prediabetic states. The low acute insulin response to intravenous glucose has been proposed as a marker of both pre-Type 1 and pre-Type 2 (non-insulin-dependent) diabetes. In order to test the rel
Of 23 patients with non-insulin-dependent diabetes mellitus (NIDDM), whose fasting blood glucose had not reached less than or equal to 6.0 mmol.l-1 after 10 weeks of dietary regulation, 15, who had had a weight reduction of -2.8 kg by dietary control, did achieve a fasting blood glucose less than or