B-cell epitopes of varicella-zoster virus glycoprotein II
✍ Scribed by A. Kjartansdóttir; E. Lycke; S. R. Norrby
- Publisher
- Springer Vienna
- Year
- 1996
- Tongue
- English
- Weight
- 389 KB
- Volume
- 141
- Category
- Article
- ISSN
- 1432-8798
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African green monkeys (Cercopithecus aethiops) were immunized with three intramuscular injections of gpI, gpII, or gpIII glycoprotein antigens of varicella-zoster virus (VZV). Antibody responses to VZV were determined by enzyme-linked immunosorbent assay (ELISA) and to simian varicella virus (SVV) b
## Abstract Varicella‐zoster virus (VZV) is well known for its propensity to cause polykaryons (syncytia) in the vesicles within infected skin. Similarly in cultured cells, VZV induces extensive syncytial formation by virus‐mediated cell‐to‐cell fusion. Statistical analyses of fusion parameters dem
Varicella-zoster virus glycoprotein E (gE) is the most abundant VZV glycoprotein on the surface of virus-infected cells. VZV gE has targeting sequences for the trans-Golgi network (TGN) and is transported from the ER to the TGN in infected and gE-transfected cells. In this study, VZV gE expressing m