B-cell activation

✍ Scribed by Stephen V. Desiderio

• Book ID: 103972887
• Publisher: Elsevier Science
• Year: 1992
• Tongue: English
• Weight: 669 KB
• Volume: 4
• Category: Article
• ISSN: 0952-7915
• DOI: 10.1016/0952-7915(92)90073-n

✦ Synopsis

Extraordinary progress has been made in refining our understanding of the B-cell antigen receptor complex, the role of protein-tyrosine phosphorylation as the key intermediary in immunoglobulin signal transduction, and in identifying candidate effectors of immunoglobulin-mediated signaling. In addition, the properties of a new group of G proteins may rekindle interest in older observations implicating such molecules as important in B-cell activation.