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B-Arrestin-dependent endocytosis of the neurokinin 1 receptor (NK1R) is required for activation of p42/44 map kinases

✍ Scribed by Kathryn A. DeFea; Zackary D. Vaughn; Olivier Dery; Nigel W. Bunnett


Book ID
119425548
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
187 KB
Volume
118
Category
Article
ISSN
0016-5085

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## Abstract Results presented in this study indicate that in human embryonic kidney 293 cells (HEK 293), the ghrelin receptor growth hormone secretagogue receptor type 1a (GHS‐R1a) activates the extracellular signal‐related kinases 1 and 2 (ERK 1/2) via three pathways. One pathway is mediated by th