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B- and T-lymphocyte micronuclei in chimney sweeps with respect to genetic polymorphism for CYP1A1 and GST1 (class Mu)

✍ Scribed by Ulrika Carstensen; Anna Karin Alexandrie; Benkt Högstedt; Agneta Rannug; Ingrid Bratt; Lars Hagmar

Book ID
113194308
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
689 KB
Volume
289
Category
Article
ISSN
0027-5107

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## Abstract Tobacco smoking and occupation are major risk factors of bladder cancer via exposure to polycyclic aromatic hydrocarbons (PAHs) and aromatic amines. Glutathione S‐transferase (GST) M1, T1 and P1 are involved in the detoxification of PAH reactive metabolites. Two __N__‐acetyltransferase