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Aβ-induced Ca2+ influx regulates astrocytic BACE1 expression via calcineurin/NFAT4 signals

✍ Scribed by Seok Min Jin; Hyun Jin Cho; Yong Woo Kim; Ji Yeon Hwang; Inhee Mook-Jung


Book ID
116303811
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
827 KB
Volume
425
Category
Article
ISSN
0006-291X

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## Abstract Interleukin (IL)‐1β has been shown to induce matrix metalloproteinase (MMP)‐9 expression through mitogen‐activated protein kinases, including JNK, in rat brain astrocyte‐1 (RBA‐1) cells. However, little is known about whether JNK activated by Ca^2+^‐dependent CaMKII is associated with M