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Azotemia in cats with feline hypertrophic cardiomyopathy: Prevalence and relationships with echocardiographic variables

✍ Scribed by Vassiliki Gouni; Valérie Chetboul; Jean-Louis Pouchelon; Carolina Carlos Sampedrano; Christelle Maurey; Hervé P. Lefebvre


Book ID
104038530
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
159 KB
Volume
10
Category
Article
ISSN
1760-2734

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✦ Synopsis


Objectives:

The prevalence of renal azotemia in cats with acquired heart disease is not well documented. the aims of this study were therefore (1) to determine the prevalence of azotemia within a hospital population of cats with hypertrophic cardiomyopathy (hcm), and (2) to evaluate the relationship between echocardiographic variables and plasma urea and creatinine.

Animals, materials and methods:

134 client-owned cats were retrospectively studied including 102 cats with hcm and 32 control cats. a complete physical examination, electrocardiography, systolic arterial blood pressure measurement, thoracic radiographs, and echocardiography were performed. plasma creatinine and urea were determined in all cats. the animal was considered azotemic if plasma creatinine was >1.8 mg/dl and/or urea >65 mg/dl (i.e. bun> 30 mg/dl).

Results:

The prevalence of azotemia was lower in control cats (25.0%) than in cats with hcm (58.8%) (p=0.003). no significant differences in plasma urea and creatinine were observed between the hcm and control cats. there was no effect of plasma creatinine and urea on conventional echocardiographic variables in cats with hcm.

Conclusions:

Azotemia is a frequent finding in cats with hcm but is not dependent on echocardiographic variables.


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