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Azoles. Part 7. A convenient synthesis of thieno[2,3-d]imidazoles

โœ Scribed by Iddon, Brian; Khan, Nazir; Lim, Bee Lan


Book ID
111893602
Publisher
Royal Society of Chemistry
Year
1987
Weight
1021 KB
Volume
0
Category
Article
ISSN
1472-7781

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2,4,5-Tribromo-l-vinylimidazole was prepared from 2,4,5-tribromoimidazole and 1,2-dibromoethane and its Br-atoms were replaced regio~lectively in the order 2 --) 5 ---> 4 via Br --~ MgBr and other exchange reactions. Efficient removal of the vinyl groups from the resulting polyfunctionalized imidazo