Azoles and Azolo-Azines via 3-(3-Methylbenzofuran-2-yl)-3-oxopropanenitrile.
β Scribed by Kamal M. Dawood; Ahamd M. Farag; Hatem A. Abdel-Aziz
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 31 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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The reaction of 3-(benzothiazol-2-yl)-3oxopropanenitrile 1 with active methylene reagents 2a-d and sulfur afforded polysubstituted thiophenes 3a-c . The synthetic potential of the b-enaminonitrile moiety in 3a was explored. The reaction of 3a with active methylene reagents 2a-e afforded thieno [2,3b