A novel general method for the synthesis of oxindoles, namely the -azirine/oxindole ring enlargement via amidinium-intermediates× has been established: the reaction of 2H-azirin-3-amines 1 with BF 3 ¥ OEt 2 in THF solution at À 788 leads to 1,3,3-trialkyl-2-amino-3H-indolium tetrafluoroborates 14 in
✦ LIBER ✦
Azirine/Oxindole Ring Enlargement via Amidinium Intermediates.
✍ Scribed by Maged K. G. Mekhael; Stefan Bienz; Anthony Linden; Heinz Heimgartner
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 25 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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