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Aziridine-2-carboxylates: Preparation, Nucleophilic Ring Opening, and Ring Expansion

โœ Scribed by Ishikawa, Tsutomu


Book ID
118070791
Publisher
Japan Institute of Heterocyclic Chemistry
Year
2012
Tongue
English
Weight
1019 KB
Volume
85
Category
Article
ISSN
0385-5414

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## Abstract Ringโ€opening of __N__โ€(__tert__โ€butoxycarbonyl)aziridineโ€2โ€isopropyl carboxylate with noโ€carrierโ€added (n.c.a.) [^11^C]cyanide is reported. Following purification by HPLC, the protected D,Lโ€[4โ€^11^C]__ฮฒ__โ€cyanoalanine was subsequently hydrolysed, to yield D,Lโ€[4โ€^11^C]asparagine or D,Lโ€